Treatment of Severe Carbamazepine Intoxication with Intravenous Lipid Emulsion Therapy
نویسنده
چکیده
Carbamazepine (CBZ) is a widely prescribed anticonvulsant agent. It is used in treatment of epilepsy including general tonic-clonic, simple partial and complex partial seizures, neuropathicpains, especially in trigeminalneuralgia, central diabetes insipidus, attention-deficit and hyperactivity disorders and bipolar disorders. CBZ overdose is usually associated with cardiac, neurologic and respiratory problems. By this time, several treatment modalities such as oral multiple doses of activated charcoal, conventional hemodialysis (HD), high-flux hemodialysis (HFHD), continuous venovenous hemodiafiltration (CVVHDF), albumin-enhanced CVVHDF with high and low dialysate flow, resin hemoperfusion(HP), plasma exchange (PE) and charcoal HP have been performed in treating acute CBZ toxicity, however traditional supportive care is stil considered the primary treatment for CBZ intoxication. We would like to report a case of severe CBZ poisioning who was treated with ILE therapy.
منابع مشابه
Which is the best in carbamazepine overdose?
Intravenous lipid emulsion treatment is safer, faster, and easier to apply and could be a powerful alternative to extracorporeal treatment methods in carbamazepine intoxication.
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